Haplogroup H

Comment

Comment by Peiternella Suzzanna Hymen on May 10, 2010 at 2:35am

Heres an interesting exercise , guess what branch of H6 this following sequence is
using FTDNA mutation list and phylotree
T195C T239C A263G 315.1C A750G A1438G G3915A A4727G A4769G A8860G G9380A T10237C T11204C T11253C A15326G T16362C A16482G

Comment by Maria on April 21, 2010 at 6:39am

Well, I won't do a full sequence as I could just test around the 4336 mutation which is diagnostic for H5a according to Achilli et al. 2004.
Here's what's interesting: my boss appears to be H12 so I'll check for 3936 to make sure. I've been researching the publications on H12 and found nothing. We are a weird bunch!

Comment by Peiternella Suzzanna Hymen on April 20, 2010 at 11:28pm

Hi Maria, marine organisms hey! Interesting stuff. Handy you can do your own test...jealous LOL.Mardons comments below cover what you need to test for yourself so you can find out what H5 sub branch or clade you maybe in. H5 is cool, not to many of them guys around.Good luck in the lab and keep us posted. I am most interested to hear what you are. CHeers

Comment by Peiternella Suzzanna Hymen on April 20, 2010 at 11:20pm

Hi E Collins, I think you are wondering how the Genograhic Project defined you as an H is because you dint have the mutations 2706A, 7028C which all other haplogroups tested people have.
Your mutation 16093c is one of the
H1f 4452C, 7309C, 9066G, 16093C, 16189C however you need 3010A (this mutation defines H1. You need a full sequence, as Mardon has mentioned, to actually find out what sub branch you are in. Hope this has helped some.

Comment by Maria on April 20, 2010 at 10:24am

ok, for HVR1 i have 16111A 16304C which puts me right on H5! I did HVR2 and have the obvious 263G and 373G which is not diagnostic for anything. I'll have to get some SNPs to see if I'm H5a.
Best web I found for finding haplogroups by entering mutations is Ian Logan's!
http://www.ianlogan.co.uk/haplogroup/finder.htm
Now, I don't know about dogs as I work with marine organisms :)

Comment by Mardon Erbland on April 20, 2010 at 9:14am

E. Collins: The Genographic Project page at:
https://genographic.nationalgeographic.com/genographic/lan/en/parti...
describes that they only test HyperVariable Region 1 (HVR1, positions 16001 to 16569). They do not test HyperVariable Region 2 (HVR2, positions 00001 to 00574) nor the coding Region (CR, positions 00575 to 16000). Without a full sequence test of all the positions in your mitochondrial DNA, you will not be able to tell in which mtDNA H-subclade (if any) you belong. If you want a full sequence mtDNA test you will have to buy it from one of the labs that offers this service. I got mine at FamilyTreeDNA.com
Mardon

Comment by E Collins on April 20, 2010 at 8:19am

I recently had my mtDNA tested by the Genograhic Project and received the result that I am Haplogroup H. The only mutations listed were 16093C and 16519C. When looking at a mtDNA haplogroup chart on Family Tree DNA site, I see that different mutations are required to be H. Please help clear up my confusion.

Comment by Peiternella Suzzanna Hymen on April 14, 2010 at 3:10am

What animal DNA do you work with Maria? Interesting to see that all mtDNA for our beloved dogs is wolf. Do you know if the wolf DNA is region specific or if they can place a particular breed? Your job must be rather interesting.This DNA stuff is so fascinating and a big time waster along with distance running for me....not enough time in a day for two compulsive hobbies.
Can I ask what your mutations are, if you don't mind. I am building an H database and getting data of the papers on Phylotree -link below, another good site
.http://phylotree.org/
join and place your details and see if you get any matches, plus you may get an idea of what your sub clade maybe! Good luck

Comment by Maria on April 13, 2010 at 11:13pm

No company as I work in a genetics lab and I did it myself. Just that I work with non human DNA and I can't find a DB to enter the mutations of HVR2. HVR1 show I'm H and like you say, I don't think HVR2 will show enough resolution for a sub group. I'll check tomorrow at work. Thanks!!!

Comment by Peiternella Suzzanna Hymen on April 13, 2010 at 10:03pm

Please excuse my poor reading -I meant to say 'what' mutations not 'want' :)

• ‹ Previous
• 1
• 2
• 3
• 4
• 5
• 6
• …
• 8
• Next ›
• Page